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FDA ISSUES BLACK BOX WARNING FOR DIRECT ACTING HEPATITIS C ANTIVIRALS (DAAs) OVER CONCERNS FOR REACTIVATION OF HEPATITIS B VIRUS DURING DAA TREATMENT

THE U.S. Food and Drug Administration (FDA) has issued a black box warning for the DAAs used in the treatment of chronic hepatitis C virus. There have been reports in the literature and to the FDA of hepatitis B virus reactivation and several cases of fulminant hepatitis B in patients who are co-infected with hepatitis C virus and hepatitis B virus who begin anti-HCV DAA treatment. U.S. hepatitis C guidelines have been updated to include recommendations for hepatitis B virus testing prior initiation of DAA treatment and suppressive therapy for hepatitis B virus during DAA treatment for individuals who meet HBV treatment criteria. 

 

Influenza Resource Center
 

CDC Updates on Influenza Virus Activity in the U.S.

 

Pan American Health Organization's Influenza Situation in the Americas

 

World Health Organization's Global Surveillance

 

As the influenza season in South America is winding down, the World Health Organization is recommending that a new clade 6B influenza A H1N1 virus A/Michigan/45/2015 (H1N1) replace A/California/7/2009 (H1N1) pdm09-like virus

 

Zika Virus Resource Center

 

Preconception Counseling and Prevention of Sexual Transmission of Zika Virus for Persons with Possible Zika Virus Exposure – United States, September 2016

New Zika Virus Special Travel Considerations for 11 Southeast Asian Countries [Brunei, Burma (Myanmar), Cambodia, Indonesia, Laos, Malaysia, Maldives, Philippines, Thailand, Timor-Leste (East Timor), Vietnam] Posted by CDC

CDC Updates Guidance for Travel and Testing of Pregnant Women and Women of Reproductive Age for Zika Virus Infection Related to the Ongoing Investigation of Local Mosquito-borne Zika Virus Transmission in Miami-Dade County, Florida (HAN-00396)

MMWR Publication: Demographics and Clinical Characteristics of Children Aged 0-17 Years with Zika Virus Disease Acquired Postnatally – U.S., January 2015-July 2016

 

MMWR Publication: Preliminary Findings from an Investigation of Zika Virus Infection in a Patient with No Known Risk Factors – Utah 2016

Elsevier Zika Virus Resource Center

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