What You Should Be Reading: : Seoul virus

Outbreak of Seoul Virus Associated with Home-based Rat-breeding Facilities in Wisconsin and Illinois

Sunday, December 17, 2017   (0 Comments)
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CDC Health Advisory Network has reported an outbreak of Seoul virus first diagnosed in a home-based rat breeder in Wisconsin. Trace-in investigation demonstrated six additional human cases associated with two Illinois rat-breeding facilities that shipped rats to the Wisconsin breeder. Trace-out investigation showed that rats from affected facilities were shipped to residents of Alabama, Arkansas, Colorado, Illinois, Indiana, Louisiana, Michigan, Minnesota, South Carolina, Tennessee, and Utah. In humans, most Seoul virus infections are asymptomatic or mild. Severe disease can occur in the form of hemorrhagic fever with renal syndrome similar to other hantaviruses like Sin Nombre virus. The virus is transmitted through exposure to aerosolized urine, droppings, or dust from nests/bedding of infected rats. Detection of Seoul virus RNA in blood and serology (IgM and IgG) are useful diagnostic tests. Virology laboratories in the affected states should be aware of the potential for this infection in their care populations.



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